Saturday, July 12, 2008

Using Antibiotics Rarely and Wisely


Amoxil, generic name Amoxicillin, is a penicillin-based antibiotic. It is used to fight bacteria in the body and is prescribed for bacterial infections. Examples of such infections include bladder infections, E Coli, salmonella, gonorrhea, skin infections and ear infections. Amoxil might be used with Biaxin, or clarithromycin, to treat stomach ulcers resulting from a Helicobacter pylori infection. Prevacid, or lansoprazole, is a stomach acid reducer, also commonly prescribed in such cases.

Amoxil will not treat flu or the common cold. It is sometimes used before dental work or surgery to prevent infection. When treating conditions such as strep throat, it is vital to take the whole course of antibiotics, even if you feel better, to make sure the bacteria is totally eradicated.

It is unsuitable if you are allergic to penicillin or cephalosporin antibiotics, have a kidney or liver disease, have asthma or hay fever or any blood problem. Amoxil can reduce the efficacy of contraceptive pills so you should take extra precautions whilst using it. It is not recommended to breast feed while taking Amoxil. The doctor might want to take a swab to see if your illness is susceptible to Amoxil or whether a different medication would be better, before prescribing anything.

Amoxil should be taken with liquid such as milk, water or fruit juice, and can be taken either with or without food. Side effects include diarrhea, nausea, a headache, having to urinate more or less than usual, vaginal irritation and flu-type symptoms. More serious side effects include vomiting, feverishness, wheezing and blacking out, but these are quite rare.

Amoxil is widely available and comes as a powder to mix with water, tablets or chewable pastilles. If you are ill, it is always best to consult a doctor rather than self-medicate, although Amoxil is widely available online. Put amoxil into a search engine such as Google and you will see many websites where you can order it.

This drug can interfere with beneficial, healthy bacteria in the colon, so you should only take it for prolonged periods if your doctor tells you to. Your natural resistance to antibiotics can increase if you take antibiotics too frequently or for a long time.

Because of possible side effects and contraindications, it is a good idea to talk to your doctor, or at least a pharmacist, before attempting to buy Amoxil online. A course of the antibiotic online will cost you at least $70 and it might not even be suitable for the particular illness you have.

Another thing to bear in mind is that when you order online, you risk ordering counterfeit drugs from fraudulent sellers. The drugs might be out of date or fake. You should be wary about ordering online if there is no address or telephone number for the online company or if their drug prices are a lot lower than those of the competition.

Many of these websites operate from outside of the United States. It is always best to seek a medical opinion first, to find out whether Amoxil is the best drug to treat you, and to get a legitimate prescription for the correct drugs.

You can buy Amoxil here

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Arkaig_Roe's weblog

A Urinary Tract Infection (UTI)


UTI or a urinary tract infection is a bacterial infection that has an effect on any part of the urinary tract. UTI are a critical health problem distressing millions of individuals every year.

Infections of the urinary tract are the second most usual sort of infection in the body. They involve roughly 8.3 million doctor visits every year. Women are in particular apt to UTIs for causes that are not yet well known. In her lifetime, one woman in five grows a UTI. UTIs in men can be so critical when they do take place although not as usual as in women.

Urine typically does not have bacteria in it, though it includes various fluids, salts, and waste products. They will lead to a UTI when bacteria get into the bladder or kidney and multiply in the urine.

There are three major types of UTI. Bacteria that infect simply the urethra bring about urethritis. Bacteria can bring about a bladder infection as well, which is named cystitis. Another sort of UTI is infection of the kidney itself, more critical, recognized as pyelonephritis. An individual frequently suffers back pain, high fever, and vomiting with this type of UTI.

Due to changes in the immune system, individuals with diabetes possess a higher risk of a UTI. Any other confusion that represses the immune system increases the risk of a urinary infection.

In simple UTI, the urinary tract has no structural abnormality, the renal function is normal and you have no related disease which damages defence mechanisms. But in convoluted UTI, the urinary tract is abnormal because of obstacle or kidney disorders, or there is a related disease that inclines to it like diabetes mellitus.

In a good number of cases, UTIs can be dealt with effectively with no leading to kidney damage. If the problem is not corrected and the infection continues, UTIs affected by a kidney stone or an enlarged prostate gland can harm the kidneys. If not treated punctually, UTIs in young children can at times lead to kidney damage as well.

UTIs are dealt with antibacterial drugs. The selection of drug and time-span of treatment rely on the patient's history and the urine tests that detect the felonious bacteria. The sensitivity test is particularly helpful in assisting the doctor choose the most valuable drug.

The drugs most frequently employed to deal with routine, uncomplicated UTIs are trimethoprim (Trimpex), trimethoprim/sulfamethoxazole (Bactrim, Septra, Cotrim), amoxicillin (Amoxil, Trimox, Wymox), nitrofurantoin (Macrodantin, Furadantin), and ampicillin (Omnipen, Polycillin, Principen, Totacillin). In recent years a group of drugs called quinolones contains four drugs accepted for treating UTI. These drugs consist of ofloxacin (Floxin), norfloxacin (Noroxin), ciprofloxacin (Cipro), and trovafloxin (Trovan).

You can buy Trimox here

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darkcow's weblog

Thursday, July 10, 2008

Breast Cancer Metastatised to Liver After Surgery, Chemotherapy ...


Chan’s daughter told us that her mother’s loss of blood was due to the bleeding from her guts. The doctor in the private hospital told the family that nothing much could be done since the cancer had spread. Chan is a worrying-type of person and suffered from the following:

• She has pains if she walks for some distance.


• She is not able to sleep when she feels “heaty”.


• When she is asleep, she observes that her stomach moves and churns.


• Her stools are black in colour.

In December 2006 (about a year after taking Arimidex), Chan suffered a sudden onset of pains throughout her body besides having shortness of breast. Then, her guts bled leading to severe loss of blood. Are these problems related to the intake of Arimidex?

Among the many documented side effects of Arimidex are: hot flushes, mood disturbances, depression, fatigue, nausea and vomiting, muscle and bone pain, shortness of breath or coughing, fractures due to reduction of bone density, thromboembolic events, rash, swelling or water retention, loss of appetite, weight gain, constipation, diarrhea, vaginal bleeding and gastrointestinal disorder.

In spite of the above the medical researchers concluded that the use of Arimidex is “well tolerated”. To get an insight of what patients suffer, go to the message board of cancercompass (link below).

Patient 1 wrote: I have been on Arimidex for almost two years now. Firstly I had hardly any side effects and slowly but surely they seem to be building up, some days far worse than the next. The main side effects which I am experiencing now are aching bones and joints, mainly while trying to sleep at night. Also tiredness and seem to want to just go to bed to rest from as early as 8 p.m. -- this is sad as I always went to bed late before my breast cancer.

Patient 2 wrote: I have been on Arimidex for three and a half years. I too, did not notice anything in the beginning but am now beginning to wonder. I always seemed to have trouble standing for longer periods of time -- seemed to always want to sit down instead. Last summer (August) I had trouble walking for any amount of time over 20 minutes. In February of this year I had a major back trouble with sciatica. It was very, very bad. My Radiation Oncologist mentioned that maybe it was a side effect of the Arimidex. I also wake up four to five times every night.

Patient 3 wrote: I began taking Arimidex in late June and from the beginning had a constant headache, very slight so I didn't worry too much. Then the bone pain started and got worse very quickly. My oncologist wanted me to switch to "something else" right away.

Patient 4 wrote: My pains are definitely getting worse as each month goes by. I wake up feeling 30 years older. I am with pains pretty much all over the bones and joints from the hips down! I get depression too, very bad at times. Not sure if this is because I lack sleep due to painful nights, feeling sorry for myself or the effects of Arimidex.

Patient 5 wrote: Like you, at first I didn't notice any side effects. But for the last two to three 3 years I've experienced severe pain in my neck and back, specifically in the thorax region. It is truly debilitating at times. My doctor told me it was degenerative arthritis. But as I read your and other women's remarks who are on this treatment, I have to wonder if it is the Arimidex.

Patient 6 wrote: I just started taking this drug in June. At fist I was fine but recently I've been having pains. I wake up several times at night with pains in my arms and fingers.

Patient 7 wrote: I have been on this medication for seven months. I too have much joint pain -- pain during the night that wakes me up! I am wondering if it is worth all this pain -- there is no guarantee that in five years the breast cancer will not return!

Patient 8 wrote: I have been taking Arimidex for two years also. I feel bone pain, my hands hurt, my headaches have gotten worse, I am depressed, and my appetite is just not there any more. I wake up three hours after I go to bed. I feel tired and drained the rest of the day. My doctor thinks I am a hypochondriac. But these symptoms are real. My cousin had been taking this for four years and her intestine got infected from all the medicine. It started to eat away at it. She died two months after the removal of her intestine. Have you heard any thing about that?

The comments of these patients and the case presented by Chan are real. These are not fantasies of the patients’ mind. The side effects suffered by Chan are similarly felt by other patients. Chan had bleeding from her guts. Reading the comment of Patient 8, who wrote that her cousin who took the drug for four years, ended with an “eaten away” gut, one cannot help thinking if Arimidex is causing similar problem to Chan’s gut.

It is most distressful to see the CT scan of Chan’s liver. The metastasis is so extensive and widespread covering her entire liver. Over the decades looking at liver images, I cannot help feeling that the scan images of Chan’s liver is rare indeed.

The question that begs an answer: “Why is the liver metastasis so extensive?” Only a year ago (April 2006) Chan’s liver was said to be free of metastasis. Why does this happen so suddenly and so soon? It is understandable if there are only one or a few metastatic spots in her liver but to have numerous nodules at once is beyond comprehension. One is tempted to ask if this metastasis could be related to the treatment rather than the cancer itself.

The case of Chan further reinforces my resolve to say this to cancer patients: Cure for cancer requires a change of diet, lifestyle and full commitment on the part of patients to take matters into their own hands. Subjecting themselves to invasive treatments of modern medicine and taking of the so-called “FDA-approved drugs” may not be the only option for them. Look far and wide – there are other options available in the horizon. My experience shows that for some patients, taking the “alternative, holistic” path could prove to be a more humane and effective path for their cancers.

You can buy Arimidex here

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Findus's weblog

Day Trading Stock Symbols - How To Decipher The Cryptic Day ...


Ticking symbols refer to the letter system which are representative of the stocks. They are needed to monitor and find security info. It is useful if you are offering a quote because you might be asked to enter a symbol for the transaction. These numbers and letters contain vital security information

The tick symbol of a mutual fund is composed of five letters that end with an "X". A prime example is FMAGX which represents Fidelity Magellan fund and the VFINX represents Vanguard's Index Five Hundred fund. If this acts as the funds on the money market, three letters ending with an 'X' are used instead..

Stock symbols which are listed on the NYSE or AMEX exchanges consist of three bills of exchange, while the Nasdaq uses four letters. But 5 letters are made use of in the case of Nasdaq when the stock contains more than 1 issue of a common stock, where the fifth letter would have a defined meaning.

The 5th letterticker symbols and what they mean.

A for Class A, B for Class B, C for Class C except for the issuer of qualification, the new edition by D, E on deposits SEC is delinquent, F denotes foreign, the first of convertible bonds G, H second convertible bond , I third convertible bonds, J denotes voting, K denotes Nonvoting , various situations L.

M preferred shares of the fourth class, N the preferred shares of the third class, O on preferred shares of the second class, P denotes preferred shares of the first class, the bankruptcy proceedings Q, R designates rights, S shares of beneficial interest,T denotes rights or warrants, mutual fund X, Y denotes ADR also known as American Depository Receipt, with Z for various miscellany situations.

Some stock symbols seem funny to some of us. It can be confusing when you get these symbols from your exchange.

Some of these are - AFL.BO invest a football locker room, CHIC is a trends stock, and CRZY is a title which is very volatile, CTCO.NS your money is being sought by the city of thugs , GEEK do something to oppose CHIC Stock, DABU.NS Saturday night lives must be avoided or forgotten, BNCO.NS honest focuses on the management of a company by a person.

EMCO.NS more disadvantages on a identity is moving, FUN investing stocks is both fun and play, FUSEX explanation is not necessary, GASEX mutual fund which is fighting flatulent, GODD people investing directly on future sins, suggests careful HIT because a hit decisions could be held in inventory, HUMP forget pump and dumping of stocks regimes, ICSEX speech by saying that it is lot better to see people dead or make love in Alaska, investor or IMAN MAN with a skewed sex, INSEX fund a lot of movement.

LMNE short of a title, because it could go wrong, LUV expression of what's love got to do with it, NEB. As likes stocks, stocks MORE.BO make you sweat, MRB.SN company is need for a BS_er what is good, MRFIX adding portfolio of the fund during breaks, PNSEX mutual funds strange golden shower, RATL toy manufacturer baby SRRY apologies to the stocks invested, URI multiple personalities stock WMNXX money market funds favorite by playboys and WSob stocks are becoming hot like sushi.

A little research will tell you what these symbols really mean. . Be aware, at times these symbols may be modified and changed so do remain up to date.

You can buy Gasex here

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Gnarl's weblog

Nizoral Shampoo And Hair Loss


Nizoral shampoo works well on dandruff and this prevents hair loss. There are two types of them. Nizoral mild shampoo contains 1% of ketkconazole, thereby increasing hair volume and decreasing hair fall. 2% of ketkconazole is present in anti-dandruff shampoo for treating severe dandruff problem. A research conducted found that its users shed 16% less hair compared to other shampoo users. It also increased anagen-phase hair follicles. In general, it is a fact that losing your hair is something nobody can bear to face. Losing your hair is emotionally depressing and thus hair loss is a serious issue for most of the people. Especially in females, this issue is considered to be really serious. A lot of people are concerned about this fact that hair loss is inevitable due to the diet we take these days. Our diets are not balanced and the genetically modified food is not healthy enough to ensure health. Thus people face problems li8ke hair loss. There are few natural and synthetic combats to the problem of hair loss, which can save you from this embarrassment. They are one of the best ways to combat hair loss.

Nizoral shampoos are a dandruff treatment shampoo and are never advertised as a hair fall therapy shampoo because it is not authenticated. There is no guarantee that it will give you a dandruff free scalp and thicker hair growth. Check with you dermatologist before buying the shampoo or you could end up buying expensive shampoos without reaping its benefits.

Nizoral successfully drives away itching, inflammation and simultaneously stimulates hair growth. This shampoo is available in most grocery stores and it is the only shampoo in the market that can make dandruff vanish. It is a remarkable shampoo for bringing down the DHT level in the scalp and for treating fungal infection.

Nizoral shampoo tackles dandruff and helps to overcome hair loss. Regular use of this shampoo will prevent its recurring. It should be used twice a week. This shampoo is not perfumed and pleasant and cleans the hair like any other shampoo, leaving the hair manageable and healthy.

Nizoral shampoo fights hair loss, because it basically fights injections caused by yeast or fungus. Though it is known to cure fungal infection it is popularly known as anti-dandruff shampoo. People allergic to Ketoconazole, children and aged people should use this shampoo only after consulting the physicians. Overuse of it could leave your hair looking dry, dull and arid.

These are few of the important points about Nizoral shampoos. This shampoo is a great help to those who are interested in finding a remedy to their hair loss problem. In this way the hair loss issue can be done with forever.

You can buy Nizoral here

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Lonagan's weblog

Feldene Medication - Uses and Side Effects


Feldene is nonsteroidal anti-inflammatory drug. Feldene alternative name is Piroxicam. Feldene drug that are not approved professional labeling for the drug but that may be prescribed by your health care professional. It is works by reducing hormones that cause inflammation and pain in the body and reduce the pain, inflammation, and stiffness caused by rheumatoid arthritis and osteoarthritis. It is is used to relieve the inflammation, swelling, stiffness, and joint pain. Most important fact about Feldene is few patients on long-term therapy, Feldene can cause stomach ulcers and bleeding. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication may also be used to treat other conditions including gouty arthritis, arthritis of the spine, and muscle injuries.

Feldene can also cause liver damage. Feldene has been known to damage the kidneys. Drugs such as Feldene may cause eye disturbances in some people. Feldene must not be utilised to treat pains prior to or after a CABG surgery (Coronary Artery Heart Bypass). Feldene should be taken with or after food and avoid stomach upset. The usual maximum daily dose is 20 mg. In the case of menstrual cramps, an initial dose of 40 mg is sometimes taken followed by daily doses of 20 mg for three to four days. Piroxicam suppositories are also an alternative. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. Feldene and other NSAIDs work by inhibiting the action of certain hormones that cause inflammation and pain in the body. These hormones are called prostaglandins.

Uses of Feldene Medication

Feldene Medication take Feldene with food or an antacid with a full glass of water. Take this medication exactly as prescribed by your doctor.Never take it on an empty stomach.if you take Feldene Avoid alcohol and aspirin and If you forget to take a dose, take it as soon as you remember and never take two doses at the same time. Feldene Medication Store at room temperature. Protect from light and heat.

Side Effects of Feldene Medication

Feldene common many side effects may include is abdominal pain or discomfort, anemia, constipation, diarrhea, dizziness, fluid retention, gas and vomiting. This drug may rarely cause serious (possibly fatal) liver disease. Others common or rare side effects may include is angioedema (swelling of lips, face, tongue and throat), anxiety, asthma, belching, black stools, blood in the urine, blurred vision, bruising, colicky pain, coma and confusion.

You can buy Feldene here

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Archus's weblog

Wednesday, July 9, 2008

Grapefruit Juice: The Hidden Dangers Of Drug Interaction


Grapefruit juice is one of the healthiest foods around, right?

A cup of unsweetened white grapefruit juice has only 100 calories, no fat, more than 100% of the recommended daily amount of vitamin C, and it’s got a zingy taste that can really get you moving in the morning.

However, grapefruit juice (including the juice found in your morning grapefruit half) can interact with certain medications, leading to potentially serious consequences.

Which medications does grapefruit juice interact with?

Grapefruit juice can interact with many different drugs that people take to maintain their health. If you eat grapefruit or drink grapefruit juice, you should ask your prescribing health care provider and pharmacist about any drugs that you’re currently taking and ask again whether new drugs interact with grapefruit juice. The list below contains some of the drugs that interact with grapefruit juice. This is not a complete list, so if you’re a grapefruit fan, check with your doctor before starting any medication.

* Valium (diazepam): This drug is used to treat certain seizure disorders and anxiety.

* Norvasc (amlodipine): This is one of the drugs called a “calcium channel blocker.” It is used to treat angina (chest pain related to malfunctioning arteries around the heart). Grapefruit juice interacts with many of the calcium channel blockers

* Pravachol (pravastatin): Like several of the “statin” drugs used to lower cholesterol, grapefruit juice can change the effectiveness of this product

* Cordarone (Amiodarone): This drug is used to treat “arrhythmias” – to correct irregular heart beat patterns.

What Are The Symptoms of These Interactions?

Use of any of these drugs while taking grapefruit juice can lead to serious complications. For example, the following have been observed in the interaction of each of the drugs above with grapefruit juice:

* Valium (diazepam): Grapefruit juice can cause you to feel sedated and might make it harder for you to control your muscular movements; driving can be dangerous

* Norvasc (amlodipine): Grapefruit interacts with several of the calcium channel blockers to provide a very fast heartrate (“tachycardia”) and/or a drop in blood pressure to below safe levels (“hypotension.”

* Pravachol (pravastatin): The statin drugs can interact with grapefruit juice to cause muscle toxicities, symptoms of which include muscle weakness, aches and shaking

* Cordarone (Amiodarone): Ironically, mixing this drug with grapefruit juice can cause an increase in the very condition it is intended to treat - arrhythmias

What Causes These Potentially Dangerous Interactions?

How can something as seemingly harmless as grapefruit juice affect the medications you take? It has to do with a special enzyme in your intestines and liver that help you absorb many oral drugs and then excrete them when you’re done with the drug.

When a physician prescribes a specific dose of drug (for example, one pill of 50 mg), she works on the assumption that given the size of your body, you will absorb the drug into your body at a certain rate and excrete it at a certain rate. Enzymes in your gastrointestinal (or GI) tract bring food and oral medications into your body. Grapefruit juice seems to affect both the rate of the drug coming into your body and how quickly it is removed. The end result can be an overdose of the drug) even if you’re taking the correct dosage for your size.

What Can I Do To Avoid Dangerous Drug Interactions?

If you are on medications that interact with grapefruit juices, avoid eating grapefruit or drinking grapefruit juice. Spacing out the drugs and the juice (for example, taking your medication at night and having grapefruit for breakfast) will NOT solve the problem; the grapefruit juice effect remains even after you’ve stopped having it. If you like the health benefits of grapefruit, or just miss that morning zing, think about moving to other fruits such as tomatoes (a single can has just 41 calories and more than 70% of the vitamin C for the day) or oranges.

Kharasch, E. “Influence of hepatic and intestinal cytochrome P4503A activity on the acute disposition and effects of oral transmucosal fentanyl citrate,“ Anesthesiology, Volume 101, issue 3, pages 729-737, 2004

Maskalyk, J., “Grapefruit juice: potential drug interactions,” Canadian Medical Association Journal, Volume 167 issue 3, p 279-80, 2002

Shapiro, L, “Drug interactions: Proteins, pumps, and P-450s,” Journal of the American Academy of Dermatology, Volume 47, issue 4, pages 467-84, 2002

You can buy Norvasc here

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Kaydis's weblog

Colchicine Recall - Colchicine Side Effects & Colchicine Lawsuits


Drug manufacturer ApotheCure and the Food and Drug Administration enacted an immediate recall of compounded Injectable Colchicine .5mg/ml, 4ml vials, lot number 20070122@26 due to three recent deaths in Oregon. ApotheCure, a pharmacy based in Texas, recently mistakenly made this batch of an already dangerous drug 10 times stronger than the label stated. Colchicine is an extremely toxic nitrogen-based medication used by doctors to treat a number of conditions such as:

• Gout: Gout is caused when uric acid builds up in the cartilage of the tendons or joints throughout the body, which inflames the tissues and results in immense pain. Colchicine gout treatment side effects are extremely dangerous unless the drug is administered carefully


• Secondary amyloidosis(AA): This condition occurs when protein deposits build up in the body


• Scleroderma: When collagen builds up the skin or other organs it can cause scleroderma, which can be fatal in some cases


• Familial Mediterranean fever: This autoimmune disease affects people with ancestry primarily from around the Mediterranean Sea, and affects a wide number of systems including the chest, lungs, skin, and abdomen.

This recall is very similar to a recall that occurred in 2000 when Phyne Pharmaceuticals of Scottsdale, Arizona accidentally labeled their injectable colchicine .5 mg/mL, but it was actually the far more potent and potentially fatal 5 mg/mL.

Three people in Oregon have already died due mislabeled compounded colchicine. Compounding is a process that pharmacies sometimes use to create medications for people that have certain conditions that prevent them from using standard drugs. ApotheCure Inc. compounded colchicine for the Oregon patients, but made it too strong. Colchicine is already extremely dangerous under the right conditions, but when it is used incorrectly it can be almost immediately life-threatening. ApotheCure Inc. initiated a recall in order to prevent more fatalities from occurring.

Colchicine poisoning side effects include:


• Fatigue


• Weakness


• Sore throat


• Rash


• Numbness


• Allergic reactions such as hives, swelling of lips/face/tongue, closing of throat, difficulty breathing


• Unsuspected bleeding and bruising

The most serious colchicine side effects include:

• Fetal damage in pregnant women


• Anemia,


• Respiratory failure


• Kidney failure


• Death

You can buy Colchicine here

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Redwizard's weblog

Is This High Blood Pressure Medicine Right For You?


What is Aldactone?

Aldactone (generic name: Spirionolactone) is a water pill (diuretic) and antiandrogen. The medicine is also marketed under other names such as Novo-Spiroton, Spirotone, Spiractin and Berlactone.

Aldactone is known as a potassium-sparing diuretic, as the term suggests, this medication keeps your potassium levels from getting too low while preventing your body from absorbing too much salt .

While regularly prescribed for high-blood-pressure patients, the drug can also be prescribed along with other drugs. However, the drug is useful only for controlling, rather than curing, high blood pressure. Aldactone has to be taken regularly for its effect to become apparent. Blood pressure cannot be brought under control quickly. It is also advisable to keep using Aldactone even after you have started feeling better.

Aldactone also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome. This medication is also used to treat or prevent hypokalemia (low potassium levels in the blood).

What is Aldactone prescribed for?

Aldactone is also used for the diagnosis as well as the treatment of Hyperaldosteronism. This is a condition in which you have too much aldosterone in your body. Aldosterone is a hormone produced by your adrenal glands to help regulate the salt and water balance in your body. Excessive amounts of Aldosterone can increase the fluid retention in the body and is a contributing factor of high blood pressure or hypertension.

Precautions

The safety and effectiveness of Aldactone is dependant upon a strict adherence to a medication schedule and should never be used without a prescription and consultation of your doctor. To avoid any complications and possible worsening of the condition it is essential to follow a specific schedule for dosage and avoid any sudden discontinuation of the drug. If a dose is missed, Aldactone should be taken as soon as possible, however, doubling-up on the dosage can be dangerous and is not recommended.

Certain foods should be avoided while taking the medicine. In case of surgery or other medical emergencies, the doctor should be informed beforehand about the usage of the drug.

What are the Side effects?

Because aldactone is designed to alter the levels of potassium in your system, some side effects may occur as your body adjusts to these changes. These may include symptoms such as excessive thirst and dry mouth, arrythmia, cramps or muscle pain all conditions related to the change in the levels of potassium in the body.

Other potential side effects may include breast development in among male users, deepening of voice, excessive hairiness, irregular menstruation, fever, headache, diarrhea, drowsiness, bleeding or inflammation of the stomach and liver, and skin problems.

Last word

Patients who have problems related to the heart, kidney or liver, and a high level of potassium in the blood should not be prescribed the drug.

Do not start using a new medication without telling your doctor. If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms but can be treated effectively without adversely affecting your active lifestyle.

You can buy Aldactone here

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darkcow's weblog

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Review


Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly prescribed categories of drugs worldwide in the treatment of pain and inflammation in many conditions.

NSAIDs are used primarily to treat inflammation, mild to moderate pain, and fever. Specific uses include the treatment of headaches, arthritis, sports injuries, and menstrual cramps. Aspirin is used to inhibit the clotting of blood and prevent strokes and heart attacks in individuals at high risk. NSAIDs also are included in many cold and allergy preparations. Two drugs in this category, ibuprofen and naproxen, also reduce fever.

Uses

NSAIDs are usually indicated for the treatment of acute or chronic conditions where pain and inflammation are present. These drugs also are effective in some neuropathic pain syndromes when used with other analgesics. NSAIDs are generally indicated for the symptomatic relief of the following conditions:


  • Rheumatoid arthritis

  • Osteoarthritis

  • Acute gout

  • Inflammatory arthropathies (e.g. ankylosing spondylitis, psoriatic arthritis, Reiter's syndrome)

  • Dysmenorrhoea (painful menstruation)

  • Headache and migraine

  • Postoperative pain

  • Mild-to-moderate pain due to inflammation and tissue injury

  • Back pain and sciatica.

  • Sprains, strains, and rheumatism.

  • Dental pain.

  • Pain from kidney stones (renal colic).

  • To reduce fever

  • Other painful conditions, especially where there is inflammation.




Drugs In The Class

There are several different types of NSAIDs:


  • Salicylates: aspirin (Ascriptin, Bayer, Ecotrin), diflunisal (Dolobid, Diflunisal Tablets), salsalate (Argesic SA, Disalcid, Salflex, Salsitab, Mono Gesic)

  • Arylalkanoic acids: diclofenac (Voltaren, Cataflam), indomethacin (Indocin)

  • 2-Arylpropionic acids (profens): ibuprofen (Motrin, Advil), ketoprofen (Orudis, Oruvail), naproxen (Naprosyn, Alleve), carprofen

  • Pyrroles: ketorolac (Toradol)

  • Enolic acids (oxicams): piroxicam (Feldene), meloxicam (Mobic)

  • Sulphonanilides: nimesulide

  • Napthylalkanones: nabumetone (Relafen)




Mechanism Of Action

NSAIDs work by suppressing the production of fatty acids called prostaglandins that cause inflammation and pain. They do this by blocking the action of an enzyme, cyclooxygenase (COX). This enzyme is responsible for converting precursor acids into prostaglandins.

In the periphery NSAIDs work by decreasing the sensitivity of the nociceptor to painful stimuli induced by heat, trauma, or inflammation. In the central nervous system, they are thought to function as antihyperalgesics and block the increased transmission of repetitive incoming signals to higher centers. In effect, they modulate perception of pain caused by repetitive stimulation from the periphery.

Differences Between NSAIDs

NSAIDs vary in their potency, duration of action, and the way in which they are eliminated from the body. Another important difference is their ability to cause ulcers and promote bleeding. The more an NSAID blocks Cox-1, the greater is its tendency to cause ulcers and promote bleeding.

Choice of NSAID for chronic and disabling inflammatory joint diseases like rheumatoid arthritis and osteoarthritis is governed by age, diagnosis, degree of severity, relative gastrointestinal safety, tolerability, and relative efficacy in the given clinical situation. It is a common misconception that all NSAIDs are therapeutically equally efficacious and any one of them could be used for the given indication. Use of multiple NSAIDs should be discouraged. An agent with comparatively less gastrointestinal (GI) side effects like ibuprofen and diclofenac should be preferred in place of indomethacin, piroxicam, or naproxen, which are more gastrotoxic. In conditions where diagnosis is uncertain, the medicine should be empirically chosen and given for a week or so and if the response is adequate it should be continued until side effects mandate its withdrawal. Ankylosing spondylitis responds better to a particular NSAID like indomethacin. It is probably related to its stronger inhibition of prostaglandin synthesis.

Aspirin is a unique NSAID, not only because of its many uses, but because it is the only NSAID that is able to inhibit the clotting of blood for a prolonged period (4 to 7 days). This prolonged effect of aspirin makes it an ideal drug for preventing the blood clots that cause heart attacks and strokes. Most other NSAIDs inhibit the clotting of blood for only a few hours.

The major NSAIDs of potency comparable to opioids are diclofenac and ketorolac. Moderate postoperative pain, for example, may be managed using these agents. The overall analgesic effect of 30 mg of ketorolac is equivalent to that of 6 to 12 mg of morphine. Efficacy has been demonstrated for postsurgical pain including oral, orthopedic, gynecologic, and abdominal procedures. Efficacy for acute musculoskeletal pain has also been shown. Ketorolac causes ulcers more frequently than any other NSAID and is, therefore, not used for more than five days.

Naproxen provides effective relief in acute traumatic injury and for acute pain associated with migraine, tension headache, postoperative pain, postpartum pain, pain consequent to various gynecologic procedures, and the pain of dysmenorrhea.

Possible Side Effects

NSAIDs are associated with a number of side effects. The two main adverse drug reactions, associated with NSAIDs relate to gastrointestinal effects and renal effects of the agents. These effects are dose-dependent, and in many cases severe enough to pose the risk of ulcer perforation, upper gastrointestinal bleeding, and death, limiting the use of NSAID therapy.


  • Gastrointestinal adverse reactions. The most common risk of NSAIDs is that they can cause ulcers and other problems in your esophagus, stomach, or small intestine. Common gastrointestinal side effects include: nausea, dyspepsia, vomiting, diarrhea, gastric ulceration/bleeding. Risk of ulceration increases with duration of therapy, and with higher doses. To help protect the stomach, NSAIDs should always be taken with food or directly after a meal.

  • High Blood Pressure and Kidney Damage. NSAIDs reduce the blood flow to the kidneys, which makes them work more slowly. When your kidneys are not working well, fluid builds up in your body. The more fluid in your bloodstream, the higher your blood pressure. If you take NSAIDs in high doses, the reduced blood flow can permanently damage your kidneys.

  • Allergic Reactions. NSAIDs can also cause extreme allergic reactions. People with asthma are at a higher risk for experiencing serious allergic reaction to NSAIDs. Many specialists recommend that people who have asthma stay away from any NSAID, especially if they have sinus problems or nasal polyps.




Use of aspirin in children and teenagers with chicken pox or influenza has been associated with the development of Reyes's syndrome. Therefore, aspirin and nonaspirin salicylates (e.g. salsalate) should not be used in children and teenagers with suspected or confirmed chicken pox or influenza.

Indomethacin, ketoprofen and piroxicam appear to have the highest prevalence of gastrointestinal adverse drug reactions, while ibuprofen (lower doses) and diclofenac appear to have lower rates.

Serious side effects are especially likely with one nonsteroidal anti-inflammatory drug, phenylbutazone. Patients of age 40 and over are especially at risk of side effects from this drug, and the likelihood of serious side effects increases with age.

Precautions And Contraindications

NSAIDs cannot be used in the following cases:


  • Allergy to aspirin or any NSAID

  • Aspirin should not be used under the age of 16 years

  • During pregnancy

  • During breast feeding

  • On blood thinning agents (anticoagulants)

  • Suffering from a defect of the blood clotting system (coagulation)

  • Active peptic ulcer




Cost

Numerous NSAIDs are available as generics: diclofenac, etodolac, fenoprofen, flurbiprofen, ibuprofen, indomethacin, ketoprofen, meclofenamate, naproxen, piroxicam, sulindac, and tolmetin. Only meloxicam (brand name: Mobic), nabumetone (Relafen), and oxaprozin (Daypro) are available by brand name only. Generic medications may be an equally effective and less expensive treatment option.


Conclusions

All NSAIDs are similarly effective. The choice of which NSAID to try first is usually empiric. If one doesn't provide adequate pain control, try switching to another. All NSAIDS when used chronically can be associated with the development of ulcers. Differences in adverse effects seem to exist between different NSAIDs. Follow with your doctor closely and watch for signs or symptoms of gastrointestinal bleeding such as stomach pain and blood in the stools. Some NSAIDs are available in extended-release formulations that require less frequent dosing.

You can buy Mobic here

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HafhandBludson's weblog

Tuesday, July 8, 2008

Accutane, The Good and The Bad


Accutane is patented by the well-known drug manufacturer Roche Pharmaceuticals. In the United States, it goes by the brand name of Isotretinoin. In other countries, Accutane is known as Roaccutane. Some generic versions are also now available. These are known as Amnesteem, Sotret and Claravis.

Isotretinoin is derived from the A vitamin very much like Retin-A, but unlike Retin-A, isotretinoin is taken orally rather than used on the skin. Vitamin A has been proven to be very healthy for the skin but the unfortunate aspect is that the human body doesn't always assimilate vitamin A very well. In addition, if taken in large amounts, it can build up to dangerous levels. These toxins then can cause serious side effects. This fact has caused the medical professionals to exercise caution.

Isotretinoin on the other hand is very effective in battling acne because it is the only medication that works in many ways. It reduces the size of the sebaceous glands, decreases cellular accumulation, eliminates bacteria and lessons inflammation. Another positive attribute of isotretinoin is that it continues to exhibit productive results well after the individual stops using it. This drug may have a long lasting, positive effect on the skin and in the curing of the nasty symptoms associated with acne.

Accutane's most frequently experienced side effects usually involve the skin. An individual's skin may become very dry and quite irritated. The mucus membranes may also feel very much the same. One's lips and or eyes may also become extremely dry and irritated. Some other side effects might be muscle pain, joint pain, headaches, or the thinning of hair.

There are other more serious side effects, which do seem to disappear once the medication is no longer taken. These may include colitis, loss of night vision, or hepatitis.

The most serious and permanent side effect that has occurred is the damage to the unborn child of a pregnant mother. Our medical professionals are well aware of the potential birth defects to the fetus. The Accutane warnings have always and still do indicate this unfortunate fact. The potential of birth defects cannot be underestimated. The risks are very high for the fetus and can be devastating even with the usage of very small doses.

Many women experience miscarriages while taking isotretinoin. The fact is that the numbers may as high as four out of ten pregnancies are terminated in this fashion. Consequently, many groups have petitioned for this drug to be taken off the market.

If a child is carried full term, the types of birth defects are numerous and varied. A few are facial and nervous system deformities, mental retardation, or severe learning and developmental disabilities. Some of these defects or disabilities have an effect on a child's IQ, which obviously can be a life long challenge.

The prescribing of Accutane is more involved than many other drugs. There are specific steps the physician must take before the prescription can be written. The patient must also go through a series of tests. She must agree to use birth control and undergo pregnancy tests.

These steps are all for the benefit of the unborn child. As good as Accutane can be in curing acne, it can be just as devastating to the fetus. Much caution must be exercised before prescribing and using.

You can buy Accutane here

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darkcow's weblog

ACE Inhibitor High Blood Pressure Medication


Zestril, also known as Lisinopril for its generic name, is classify under a group of drugs called ACE inhibitor. ACE is the acronym for angiotensin converting enzyme.

Zestril Information

The medication is used to treat high blood pressure (hypertension), improve heart condition after a heart attack and congestive heart failure. In addition, Zestril may be used to treat certain kidney problems. The main culprit that causes high blood pressure is a chemical called Angiotensin II. If you want to prevent your blood pressure from increasing, you need to stop the production of angiotensin II.

So, as an ACE inhibitor, this is able to inhibit activities that is responsible for producing angiotensin II. Hence, your blood pressure will drop and kept well under controlled.

Common Usage of Zestril

* Treatment of hypertension

* Prevents heart attack and strokes

* Improve conditions of your heart after an heart attack

Before You Take Zestril

You should only take the drug according to your doctor's advice and recommendation. Usually, Zestril is taken once daily. You may take the medication with or without food. If you need to undergo surgery during your treatment, please consult your doctor before-hand to checkwhether you need to stop taking the medicine.

Precautions

Zestril will cause dizziness, so avoid driving or operate any machinery. You should not take any alcohol while you are on this medication. To preventing yourself from dehydrating, please in-take sufficient water to replenish your body's fluid.

If you suffer from diabetes I or blood vessel diseases such as lupus, scleroderma etc, you should not take it. Also, if you are allergic to any of the ingredients of Zestril, you should not take the medication.

Zestril Side Effects

Side effects are normally mild that include dizziness, headache, vomiting, nausea, and diarrhea. In some rare instances, serious side effects may occur and include:

* reduced sexual ability

* fainting

* change in urinating patterns

* abdominal pain

* chest pain

* rashes

If you feel that you are experiencing any of the side effects above, please seek for medical help immediately.

You can buy Zestril here

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Eversore Garlaxiel's weblog

Complementary and Alternative Treatments for Urinary Incontinence


Treatment for incontinence depends on what is causing the condition. For example, if a prostate gland problem is the cause, treatment for that condition can cure incontinence. In severe cases, an artificial sphincter, which allows you to control its open and closed settings, can be surgically implanted. Collagen injection therapy-where in collagen is injected into the external bladder to add bulk to the urethra is effective in some cases for women with sphincter deficiency and for men who experience urinary stress incontinence after prostate surgery. Medication also may be prescribed to treat incontinence; commonly prescribed drugs are anticholinergic agents (Pro Banthene), alpha-adrenergic agonist drugs, tricyclic antidepressant drugs, and antispasmodics (Bentyl, Ditropan, and Urispas). Postmeonpausal women with stress incontinence may benefit from estrogen either orally or by applying a cream to the vagina.

Complementary and Alternative Treatments

Ayurvedic Medicine

Ayurveda views incontinence as a vata disorder that's caused by a weak bladder sphincter. Your Ayurvedic practitioner may recommend taking an Indian herbal blend containing ashwagandha and also may suggest eliminating or reducing your intake of alcohol and coffee and other caffeine-containing foods, which intensify the urge to urinate as well.

If symptoms persist, see your doctor for evaluation and assistance.

Bodywork and Somatic Practices

Oriental bodywork, reflexology, massage, Therapeutic Touch, Reiki, polarity therapy, and CranioSacral Therapy are helpful first options.

Traditional Chinese Medicine

Acupuncture Chinese medical experts believe that incontinence is caused by a lack of energy in the kidney and spleen and their related meridians. To combat this imbalance, they work on the points that correspond to these areas and to the bladder.

Acupressure Points that may be focused on during an acupressure session to treat incontinence are Conception Vessel 2, Spleen 6, and related auricular points.

Chinese Herbal Therapy Herbs may be given to help tone the kidney and spleen and to strengthen bladder functions.

Yoga and Meditation

Exercise is always beneficial for strengthening muscles, including those of the bladder and surrounding areas. Try these easy yoga exercises several times daily to combat incontinence: Ashwini Mudra and Stomach Lock. Consult a trained practitioner for proper technique. Avoid these poses if you're pregnant.

You can buy Urispas here

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chakkorsis's weblog